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Crystal structure of a near-full-length archaeal MCM: Functional insights for an AAA+ hexameric helicase

The minichromosome maintenance protein (MCM) complex is an essential replicative helicase for DNA replication in Archaea and Eukaryotes. Whereas the eukaryotic complex consists of 6 homologous proteins (MCM2–7), the archaeon Sulfolobus solfataricus has only 1 MCM protein (ssoMCM), 6 subunits of whic...

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Detalhes bibliográficos
Main Authors: Brewster, Aaron S., Wang, Ganggang, Yu, Xian, Greenleaf, William B., Carazo, José María, Tjajadi, Matthew, Klein, Michael G., Chen, Xiaojiang S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629282/
https://ncbi.nlm.nih.gov/pubmed/19073923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808037105
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