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Continuous elimination of oxidized nucleotides is necessary to prevent rapid onset of cellular senescence
Reactive oxygen species (ROS) appear to play a role in limiting both cellular and organismic lifespan. However, because of their pleiotropic effects, it has been difficult to ascribe a specific role to ROS in initiating the process of cellular senescence. We have studied the effects of oxidative DNA...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2629241/ https://ncbi.nlm.nih.gov/pubmed/19118192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809834106 |
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