PKCη regulates occludin phosphorylation and epithelial tight junction integrity

PKCη is expressed predominantly in the epithelial tissues; however, its role in the regulation of epithelial tight junctions (TJs) is unknown. We present evidence that PKCη phosphorylates occludin on threonine residues (T403 and T404) and plays a crucial role in the assembly and/or maintenance of TJ...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Suzuki, Takuya, Elias, Bertha C., Seth, Ankur, Shen, Le, Turner, Jerrold R., Giorgianni, Francesco, Desiderio, Dominic, Guntaka, Ramareddy, Rao, Radhakrishna
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2009
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629239/
https://ncbi.nlm.nih.gov/pubmed/19114660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802741106
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker