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Whole-genome association study identifies STK39 as a hypertension susceptibility gene

Hypertension places a major burden on individual and public health, but the genetic basis of this complex disorder is poorly understood. We conducted a genome-wide association study of systolic and diastolic blood pressure (SBP and DBP) in Amish subjects and found strong association signals with com...

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Autores principales: Wang, Ying, O'Connell, Jeffrey R., McArdle, Patrick F., Wade, James B., Dorff, Sarah E., Shah, Sanjiv J., Shi, Xiaolian, Pan, Lin, Rampersaud, Evadnie, Shen, Haiqing, Kim, James D., Subramanya, Arohan R., Steinle, Nanette I., Parsa, Afshin, Ober, Carole C., Welling, Paul A., Chakravarti, Aravinda, Weder, Alan B., Cooper, Richard S., Mitchell, Braxton D., Shuldiner, Alan R., Chang, Yen-Pei C.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629209/
https://ncbi.nlm.nih.gov/pubmed/19114657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808358106
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