Whole-genome association study identifies STK39 as a hypertension susceptibility gene

Hypertension places a major burden on individual and public health, but the genetic basis of this complex disorder is poorly understood. We conducted a genome-wide association study of systolic and diastolic blood pressure (SBP and DBP) in Amish subjects and found strong association signals with com...

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Main Authors: Wang, Ying, O'Connell, Jeffrey R., McArdle, Patrick F., Wade, James B., Dorff, Sarah E., Shah, Sanjiv J., Shi, Xiaolian, Pan, Lin, Rampersaud, Evadnie, Shen, Haiqing, Kim, James D., Subramanya, Arohan R., Steinle, Nanette I., Parsa, Afshin, Ober, Carole C., Welling, Paul A., Chakravarti, Aravinda, Weder, Alan B., Cooper, Richard S., Mitchell, Braxton D., Shuldiner, Alan R., Chang, Yen-Pei C.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2009
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629209/
https://ncbi.nlm.nih.gov/pubmed/19114657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808358106
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