Combined targeting of lentiviral vectors and positioning of transduced cells by magnetic nanoparticles

Targeting of viral vectors is a major challenge for in vivo gene delivery, especially after intravascular application. In addition, targeting of the endothelium itself would be of importance for gene-based therapies of vascular disease. Here, we used magnetic nanoparticles (MNPs) to combine cell tra...

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Détails bibliographiques
Auteurs principaux: Hofmann, Andreas, Wenzel, Daniela, Becher, Ulrich M., Freitag, Daniel F., Klein, Alexandra M., Eberbeck, Dietmar, Schulte, Maike, Zimmermann, Katrin, Bergemann, Christian, Gleich, Bernhard, Roell, Wilhelm, Weyh, Thomas, Trahms, Lutz, Nickenig, Georg, Fleischmann, Bernd K., Pfeifer, Alexander
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2009
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629186/
https://ncbi.nlm.nih.gov/pubmed/19118196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803746106
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