Combined targeting of lentiviral vectors and positioning of transduced cells by magnetic nanoparticles

Targeting of viral vectors is a major challenge for in vivo gene delivery, especially after intravascular application. In addition, targeting of the endothelium itself would be of importance for gene-based therapies of vascular disease. Here, we used magnetic nanoparticles (MNPs) to combine cell tra...

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Detalhes bibliográficos
Main Authors: Hofmann, Andreas, Wenzel, Daniela, Becher, Ulrich M., Freitag, Daniel F., Klein, Alexandra M., Eberbeck, Dietmar, Schulte, Maike, Zimmermann, Katrin, Bergemann, Christian, Gleich, Bernhard, Roell, Wilhelm, Weyh, Thomas, Trahms, Lutz, Nickenig, Georg, Fleischmann, Bernd K., Pfeifer, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629186/
https://ncbi.nlm.nih.gov/pubmed/19118196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803746106
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