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Human Replication Protein A Melts a DNA Triple Helix Structure in a Potent and Specific Manner

Alternate DNA structures other than double-stranded B-form DNA can potentially impede cellular processes such as transcription and replication. The DNA triplex helix and G4 tetraplex structures that form by Hoogsteen hydrogen bonding are two examples of alternate DNA structures that can be a source...

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Bibliographic Details
Main Authors: Wu, Yuliang, Rawtani, Nina, Thazhathveetil, Arun Kalliat, Kenny, Mark K., Seidman, Michael M., Brosh, Robert M.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629141/
https://ncbi.nlm.nih.gov/pubmed/18410127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi702102d
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