Nutrient Deprivation Induces Neuronal Autophagy and Implicates Reduced Insulin Signaling in Neuroprotective Autophagy Activation

Although autophagy maintains normal neural function by degrading misfolded proteins, little is known about how neurons activate this integral response. Furthermore, classical methods of autophagy induction used with nonneural cells, such as starvation, simply result in neuron death. To study neurona...

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Detalhes bibliográficos
Main Authors: Young, Jessica E., Martinez, Refugio A., La Spada, Albert R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Molecular Basis of Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629092/
https://ncbi.nlm.nih.gov/pubmed/19017649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806088200
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