Down-regulation of GRP78 is associated with the sensitivity of chemotherapy to VP-16 in small cell lung cancer NCI-H446 cells

BACKGROUND: Chemotherapy resistance remains a major obstacle for the treatment of small cell lung cancer (SCLC). Glucose-regulated protein 78 (GRP78), an endoplasmic reticulum chaperone, plays a critical role in chemotherapy resistance in some cancers. However, whether the suppression of the chapero...

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Detaylı Bibliyografya
Asıl Yazarlar: Wang, Yingyan, Wang, Wei, Wang, Siyan, Wang, Jiarui, Shao, Shujuan, Wang, Qi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2008
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628931/
https://ncbi.nlm.nih.gov/pubmed/19087354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-372
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