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Nitrosothiol reactivity profiling identifies S-nitrosylated proteins with unexpected stability
Nitric oxide (NO) regulates protein function by S-nitrosylation of cysteine to form nitrosothiols. Nitrosothiols are highly susceptible to nonenzymatic degradation by cytosolic reducing agents. Here we show that although most protein nitrosothiols are rapidly degraded by cytosolic reductants, a smal...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2628636/ https://ncbi.nlm.nih.gov/pubmed/19101475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2008.10.013 |
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