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Nitrosothiol reactivity profiling identifies S-nitrosylated proteins with unexpected stability

Nitric oxide (NO) regulates protein function by S-nitrosylation of cysteine to form nitrosothiols. Nitrosothiols are highly susceptible to nonenzymatic degradation by cytosolic reducing agents. Here we show that although most protein nitrosothiols are rapidly degraded by cytosolic reductants, a smal...

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Bibliografski detalji
Glavni autori: Paige, Jeremy S., Xu, Guoqiang, Stancevic, Branka, Jaffrey, Samie R.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628636/
https://ncbi.nlm.nih.gov/pubmed/19101475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2008.10.013
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