Intergenerational Transmission of Glucose Intolerance and Obesity by In Utero Undernutrition in Mice

OBJECTIVE—Low birth weight (LBW) is associated with increased risk of obesity, diabetes, and cardiovascular disease during adult life. Moreover, this programmed disease risk can progress to subsequent generations. We previously described a mouse model of LBW, produced by maternal caloric undernutrit...

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Main Authors: Jimenez-Chillaron, Josep C., Isganaitis, Elvira, Charalambous, Marika, Gesta, Stephane, Pentinat-Pelegrin, Thais, Faucette, Ryan R., Otis, Jessica P., Chow, Alice, Diaz, Ruben, Ferguson-Smith, Anne, Patti, Mary-Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado: American Diabetes Association 2009
Assuntos:
Pathophysiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628621/
https://ncbi.nlm.nih.gov/pubmed/19017762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0490
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