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Selection by drug resistance proteins located in the mitochondria of mammalian cells

Transformation of mitochondria in mammalian cells is now a technical challenge. In this report, we demonstrate that the standard drug resistant genes encoding neomycin and hygromycin phosphotransferases can potentially be used as selectable markers for mammalian mitochondrial transformation. We re-e...

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Autors principals: Yoon, Young Geol, Koob, Michael D.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628554/
https://ncbi.nlm.nih.gov/pubmed/18721905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2008.07.004
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