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Selection by drug resistance proteins located in the mitochondria of mammalian cells

Transformation of mitochondria in mammalian cells is now a technical challenge. In this report, we demonstrate that the standard drug resistant genes encoding neomycin and hygromycin phosphotransferases can potentially be used as selectable markers for mammalian mitochondrial transformation. We re-e...

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Detalhes bibliográficos
Main Authors: Yoon, Young Geol, Koob, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628554/
https://ncbi.nlm.nih.gov/pubmed/18721905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2008.07.004
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