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Phosphorylation of GluR1, ERK and CREB During Spontaneous Withdrawal from Chronic Heroin Self-Administration

Negative motivational symptoms are observed soon after withdrawal from chronic opiate administration, and are thought to mediate dependence. Examination of brain region-specific signaling changes that accompany early withdrawal may shed light on neural mechanisms underlying negative reinforcement an...

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Detalhes bibliográficos
Main Authors: Edwards, Scott, Graham, Danielle L., Whisler, Kimberly N., Self, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628418/
https://ncbi.nlm.nih.gov/pubmed/19084907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.20601
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