Dexamethasone augments CXCR4-mediated signaling in resting human T cells via the activation of the Src kinase Lck

Dexamethasone (DM) is a synthetic member of the glucocorticoid (GC) class of hormones that possesses anti-inflammatory and immunosuppressant activity and is commonly used to treat chronic inflammatory disorders, severe allergies, and other disease states. Although GCs are known to mediate well-defin...

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Detalhes bibliográficos
Main Authors: Ghosh, Manik C., Baatar, Dolgor, Collins, Gary, Carter, Arnell, Indig, Fred, Biragyn, Arya, Taub, Dennis D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628365/
https://ncbi.nlm.nih.gov/pubmed/18840710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-04-151803
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