Overexpression of CERKL, a gene responsible for retinitis pigmentosa in humans, protects cells from apoptosis induced by oxidative stress

PURPOSE: Retinitis pigmentosa (RP), a retinal neurodegenerative disorder characterized by apoptosis of photoreceptor cells, is caused by mutations in many different genes. We analyzed the RP gene ceramide kinase-like (CERKL) to determine CERKL function and contribution to pathogenesis. METHODS: RT–P...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tuson, Miquel, Garanto, Alejandro, Gonzàlez-Duarte, Roser, Marfany, Gemma
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Molecular Vision 2009
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628313/
https://ncbi.nlm.nih.gov/pubmed/19158957
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