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Design and Evaluation of a Novel Matrix Type Multiple Units as Biphasic Gastroretentive Drug Delivery Systems

A biphasic gastroretentive floating drug delivery system with multiple-unit mini-tablets based on gas formation technique was developed to maintain constant plasma level of a drug concentration within the therapeutic window. The system consists of loading dose as uncoated core units, and prolonged-r...

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Detalhes bibliográficos
Main Authors: Lingam, Meka, Ashok, Thadisetty, Venkateswarlu, Vobalaboina, Madhusudan Rao, Yamsani
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628262/
https://ncbi.nlm.nih.gov/pubmed/19115111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-008-9173-2
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