Whi5 Regulation by Site Specific CDK-Phosphorylation in Saccharomyces cerevisiae

The Whi5 transcriptional repressor is a negative regulator of G1 cell cycle progression in Saccharomyces cerevisiae and is functionally equivalent to the Retinoblastoma (Rb) tumor suppressor protein in mammals. In early G1, Whi5 binds to and inhibits SBF (Swi4/Swi6) transcriptional complexes. At Sta...

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Autori principali: Wagner, Michelle V., Smolka, Marcus B., de Bruin, Rob A. M., Zhou, Huilin, Wittenberg, Curt, Dowdy, Steven F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2627923/
https://ncbi.nlm.nih.gov/pubmed/19172996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004300
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