FolM, A New Chromosomally Encoded Dihydrofolate Reductase in Escherichia coli

Escherichia coli (thyA ΔfolA) mutants are viable and can grow in minimal medium when supplemented with thymidine alone. Here we present evidence from in vivo and in vitro studies that the ydgB gene determines an alternative dihydrofolate reductase that is related to the trypanosomatid pteridine redu...

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Bibliographic Details
Main Authors: Giladi, Moshe, Altman-Price, Neta, Levin, Itay, Levy, Liat, Mevarech, Moshe
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Genetics and Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC262705/
https://ncbi.nlm.nih.gov/pubmed/14617668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.23.7015-7018.2003
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