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Association of Lsh, a Regulator of DNA Methylation, with Pericentromeric Heterochromatin Is Dependent on Intact Heterochromatin

The eukaryotic genome is packaged into distinct domains of transcriptionally active euchromatin and silent heterochromatin. A hallmark of mammalian heterochromatin is CpG methylation. Lsh, a member of the SNF2 family, is a major regulator of DNA methylation in mice and thus crucial for normal hetero...

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Publicat a:Mol Cell Biol
Autors principals: Yan, Qingsheng, Cho, Edward, Lockett, Stephen, Muegge, Kathrin
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2003
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262679/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14612388/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.23.8416-8428.2003
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