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Cancer cell angiogenic capability is regulated by 3D culture and integrin engagement

Three-dimensional culture alters cancer cell signaling; however, the underlying mechanisms and importance of these changes on tumor vascularization remain unclear. A hydrogel system was used to examine the role of the transition from 2D to 3D culture, with and without integrin engagement, on cancer...

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Bibliographic Details
Main Authors: Fischbach, Claudia, Kong, Hyun Joon, Hsiong, Susan X., Evangelista, Marta B., Yuen, Will, Mooney, David J.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626714/
https://ncbi.nlm.nih.gov/pubmed/19126683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808932106
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