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Copper-Induced Translocation of the Wilson Disease Protein ATP7B Independent of Murr1/COMMD1 and Rab7

Wilson disease is a genetic disorder of copper metabolism. Impaired biliary excretion results in a gradual accumulation of copper, which leads to severe disease. The specific gene defect lies in the Wilson disease protein, ATP7B, a copper-transporting ATPase that is highly active in hepatocytes. The...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Weiss, Karl Heinz, Lozoya, Javier Carbajo, Tuma, Sabine, Gotthardt, Daniel, Reichert, Jürgen, Ehehalt, Robert, Stremmel, Wolfgang, Füllekrug, Joachim
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Investigative Pathology 2008
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626389/
https://ncbi.nlm.nih.gov/pubmed/18974300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.071134
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