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Understanding the Molecular Basis of HBV Drug Resistance by Molecular Modeling

Despite the significant successes in the area of anti-HBV agents, resistance and cross resistance against available therapeutics are the major hurdles in drug discovery. The present investigation is to understand the molecular basis of drug resistance conferred by the B and C domain mutations of HBV...

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Main Authors: Sharon, Ashoke, Chu, Chung K.
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626186/
https://ncbi.nlm.nih.gov/pubmed/18765256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2008.07.010
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