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Involvement of Water in Carbohydrate-Protein Binding: Concanavalin A Revisited
Ordered water molecules bound to protein surfaces, or in protein-ligand interfaces, are frequently observed by crystallography. The investigation of the impact of such conserved water molecules on protein stability and ligand affinity requires detailed structural, dynamic and thermodynamic analyses....
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2626182/ https://ncbi.nlm.nih.gov/pubmed/19053475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja8039663 |
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