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Genetic Disruption of KSHV Major Latent Nuclear Antigen LANA Enhances Viral Lytic 2 Transcriptional Program

Following primary infection, KSHV establishes a lifelong persistent latent infection in the host. The mechanism of KSHV latency is not fully understood. The latent nuclear antigen (LANA or LNA) encoded by ORF73 is one of a few viral genes expressed during KSHV latency, and is consistently detected i...

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Bibliografiske detaljer
Main Authors: Li, Qiuhua, Zhou, Fuchun, Ye, Fengchun, Gao, Shou-Jiang
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626151/
https://ncbi.nlm.nih.gov/pubmed/18684478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.06.043
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