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Modulation of Minute Virus of Mice Cytotoxic Activities through Site-Directed Mutagenesis within the NS Coding Region

Late in infection, parvovirus minute virus of mice (MVMp) induces the lysis of mouse A9 fibroblasts. This effect depends on the large nonstructural phosphoprotein NS1, which plays in addition a major role in viral DNA replication and progeny particle production. Since the NS1 C-terminal region is su...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Daeffler, Laurent, Hörlein, Rita, Rommelaere, Jean, Nüesch, Jürg P. F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2003
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262581/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14610171/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.23.12466-12478.2003
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