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Relationship between RNA Lariat Debranching and Ty1 Element Retrotransposition
The Saccharomyces cerevisiae DBR1 gene encodes a 2′-5′ phosphodiesterase that debranches intron RNA lariats following splicing. Yeast dbr1 mutants accumulate intron lariats and are also defective for mobility of the retrotransposons Ty1 and Ty3. We used a mutagenic PCR method to generate a collectio...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC262579/ https://ncbi.nlm.nih.gov/pubmed/14610201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.23.12795-12806.2003 |
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