Viral Mimicry of Cdc2/Cyclin-Dependent Kinase 1 Mediates Disruption of Nuclear Lamina during Human Cytomegalovirus Nuclear Egress

The nuclear lamina is a major obstacle encountered by herpesvirus nucleocapsids in their passage from the nucleus to the cytoplasm (nuclear egress). We found that the human cytomegalovirus (HCMV)-encoded protein kinase UL97, which is required for efficient nuclear egress, phosphorylates the nuclear...

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Detalhes bibliográficos
Main Authors: Hamirally, Sofia, Kamil, Jeremy P., Ndassa-Colday, Yasmine M., Lin, Alison J., Jahng, Wan Jin, Baek, Moon-Chang, Noton, Sarah, Silva, Laurie A., Simpson-Holley, Martha, Knipe, David M., Golan, David E., Marto, Jarrod A., Coen, Donald M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2625439/
https://ncbi.nlm.nih.gov/pubmed/19165338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000275
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