MMSET deregulation affects cell cycle progression and adhesion regulons in t(4;14) myeloma plasma cells

BACKGROUND: The recurrent immunoglobulin translocation, t(4;14)(p16;q32) occurs in 15% of multiple myeloma patients and is associated with poor prognosis, through an unknown mechanism. The t(4;14) up-regulates fibroblast growth factor receptor 3 (FGFR3) and multiple myeloma SET domain (MMSET) genes....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Brito, Jose L.R., Walker, Brian, Jenner, Matthew, Dickens, Nicholas J., Brown, Nicola J.M., Ross, Fiona M., Avramidou, Athanasia, Irving, Julie A.E., Gonzalez, David, Davies, Faith E., Morgan, Gareth J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Ferrata Storti Foundation 2009
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2625417/
https://ncbi.nlm.nih.gov/pubmed/19059936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.13426
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