Donor-reactive CD8 Memory T Cells Infiltrate Cardiac Allografts Within 24 Hours Post-Transplant in Naïve Recipients

Normal immune responses stimulated by pathogenic and environmental antigens generate memory T cells that react with donor antigens and no currently used immunosuppressive drug completely inhibits memory T cell function. While donor-reactive memory T cells clearly compromise graft outcomes, mechanism...

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Bibliographic Details
Main Authors: Schenk, A.D., Nozaki, T., Rabant, M., Valujskikh, A., Fairchild, R.L.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2625311/
https://ncbi.nlm.nih.gov/pubmed/18557725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2008.02302.x
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