Neurons Expressing the Highest Levels of γ-Synuclein Are Unaffected by Targeted Inactivation of the Gene

Homologous recombination in ES cells was employed to generate mice with targeted deletion of the first three exons of the γ-synuclein gene. Complete inactivation of gene expression in null mutant mice was confirmed on the mRNA and protein levels. Null mutant mice are viable, are fertile, and do not...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ninkina, Natalia, Papachroni, Katerina, Robertson, Darren C., Schmidt, Oliver, Delaney, Liz, O'Neill, Francis, Court, Felipe, Rosenthal, Arnon, Fleetwood-Walker, Susan M., Davies, Alun M., Buchman, Vladimir L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC262405/
https://ncbi.nlm.nih.gov/pubmed/14585981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.22.8233-8245.2003
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados