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Akt Phosphorylation of Serine 21 on Pak1 Modulates Nck Binding and Cell Migration

The p21-activated protein kinases (Paks) regulate cellular proliferation, differentiation, transformation, and survival through multiple downstream signals. Paks are activated directly by the small GTPases Rac and Cdc42 and several protein kinases including Akt and PDK-1. We found that Akt phosphory...

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Udgivet i:Mol Cell Biol
Principais autores: Zhou, Guo-Lei, Zhuo, Ya, King, Charles C., Fryer, Benjamin H., Bokoch, Gary M., Field, Jeffrey
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2003
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262366/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14585966/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.22.8058-8069.2003
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