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The Ku Heterodimer Performs Separable Activities at Double-Strand Breaks and Chromosome Termini

The Ku heterodimer functions at two kinds of DNA ends: telomeres and double-strand breaks. The role that Ku plays at these two classes of termini must be distinct, because Ku is required for accurate and efficient joining of double-strand breaks while similar DNA repair events are normally prohibite...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bertuch, Alison A., Lundblad, Victoria
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC262345/
https://ncbi.nlm.nih.gov/pubmed/14585978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.22.8202-8215.2003
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