Molecular Characterization of the Schizosaccharomyces pombe nbs1(+) Gene Involved in DNA Repair and Telomere Maintenance

The human MRN complex is a multisubunit nuclease that is composed of Mre11, Rad50, and Nbs1 and is involved in homologous recombination and DNA damage checkpoints. Mutations of the MRN genes cause genetic disorders such as Nijmegen breakage syndrome. Here we identified a Schizosaccharomyces pombe nb...

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Bibliographic Details
Main Authors: Ueno, Masaru, Nakazaki, Tomofumi, Akamatsu, Yufuko, Watanabe, Kikuo, Tomita, Kazunori, Lindsay, Howard D., Shinagawa, Hideo, Iwasaki, Hiroshi
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
DNA Dynamics and Chromosome Structure
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC193704/
https://ncbi.nlm.nih.gov/pubmed/12944481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.18.6553-6563.2003
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