Molecular Characterization of the Schizosaccharomyces pombe nbs1(+) Gene Involved in DNA Repair and Telomere Maintenance

The human MRN complex is a multisubunit nuclease that is composed of Mre11, Rad50, and Nbs1 and is involved in homologous recombination and DNA damage checkpoints. Mutations of the MRN genes cause genetic disorders such as Nijmegen breakage syndrome. Here we identified a Schizosaccharomyces pombe nb...

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Bibliographische Detailangaben
Hauptverfasser: Ueno, Masaru, Nakazaki, Tomofumi, Akamatsu, Yufuko, Watanabe, Kikuo, Tomita, Kazunori, Lindsay, Howard D., Shinagawa, Hideo, Iwasaki, Hiroshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
DNA Dynamics and Chromosome Structure
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC193704/
https://ncbi.nlm.nih.gov/pubmed/12944481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.18.6553-6563.2003
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