Gene Dosage Effect of l-Proline Biosynthetic Enzymes on l-Proline Accumulation and Freeze Tolerance in Saccharomyces cerevisiae

We have previously reported that l-proline has cryoprotective activity in Saccharomyces cerevisiae. A freeze-tolerant mutant with l-proline accumulation was recently shown to carry an allele of the PRO1 gene encoding γ-glutamyl kinase, which resulted in a single amino acid substitution (Asp154Asn)....

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Detalhes bibliográficos

Publicado no:	Appl Environ Microbiol
Principais autores:	Terao, Yukiyasu, Nakamori, Shigeru, Takagi, Hiroshi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Physiology and Biotechnology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262311/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14602584/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.69.11.6527-6532.2003
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