Innovative Approach for Improvement of an Antibiotic-Overproducing Industrial Strain of Streptomyces albus

Working with a Streptomyces albus strain that had previously been bred to produce industrial amounts (10 mg/ml) of salinomycin, we demonstrated the efficacy of introducing drug resistance-producing mutations for further strain improvement. Mutants with enhanced salinomycin production were detected a...

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Hlavní autoři: Tamehiro, Norimasa, Hosaka, Takeshi, Xu, Jun, Hu, Haifeng, Otake, Noboru, Ochi, Kozo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
Physiology and Biotechnology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC262278/
https://ncbi.nlm.nih.gov/pubmed/14602594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.69.11.6412-6417.2003
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