Innovative Approach for Improvement of an Antibiotic-Overproducing Industrial Strain of Streptomyces albus

Working with a Streptomyces albus strain that had previously been bred to produce industrial amounts (10 mg/ml) of salinomycin, we demonstrated the efficacy of introducing drug resistance-producing mutations for further strain improvement. Mutants with enhanced salinomycin production were detected a...

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Detalles Bibliográficos

Publicado en:	Appl Environ Microbiol
Autores principales:	Tamehiro, Norimasa, Hosaka, Takeshi, Xu, Jun, Hu, Haifeng, Otake, Noboru, Ochi, Kozo
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2003
Materias:	Physiology and Biotechnology
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262278/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14602594/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.69.11.6412-6417.2003
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