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Induction of protective immunity to monoclonal-antibody-defined Plasmodium falciparum antigens requires strong adjuvant in Aotus monkeys.

Monoclonal antibodies to the major Plasmodium falciparum merozoite surface coat and rhoptry antigens were produced. A combination of the affinity-purified polypeptides with Freund complete adjuvant which was given three times completely protected an Aotus lemurinus azure (karotype VI) monkey against...

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Udgivet i:Infect Immun
Principais autores: Siddiqui, W A, Tam, L Q, Kan, S C, Kramer, K J, Case, S E, Palmer, K L, Yamaga, K M, Hui, G S
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262236/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3514459/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.52.1.314-318.1986
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