Induction of protective immunity to monoclonal-antibody-defined Plasmodium falciparum antigens requires strong adjuvant in Aotus monkeys.

Monoclonal antibodies to the major Plasmodium falciparum merozoite surface coat and rhoptry antigens were produced. A combination of the affinity-purified polypeptides with Freund complete adjuvant which was given three times completely protected an Aotus lemurinus azure (karotype VI) monkey against...

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Autores principales: Siddiqui, W A, Tam, L Q, Kan, S C, Kramer, K J, Case, S E, Palmer, K L, Yamaga, K M, Hui, G S
Formato: Artigo
Lenguaje:Inglês
Publicado: 1986
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC262236/
https://ncbi.nlm.nih.gov/pubmed/3514459
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