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Correction of obesity and diabetes in genetically obese mice by leptin gene therapy

The ob/ob mouse is genetically deficient in leptin and exhibits both an obese and a mild non-insulin-dependent diabetic phenotype. To test the hypothesis that correction of the obese phenotype by leptin gene therapy will lead to the spontaneous correction of the diabetic phenotype, the ob/ob mouse w...

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Detalhes bibliográficos
Main Authors: Muzzin, Patrick, Eisensmith, Randy C., Copeland, Kenneth C., Woo, Savio L. C.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC26217/
https://ncbi.nlm.nih.gov/pubmed/8962136
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