Mitochondrial Targeted Coenzyme Q, Superoxide, and Fuel Selectivity in Endothelial Cells

BACKGROUND: Previously, we reported that the “antioxidant” compound “mitoQ” (mitochondrial-targeted ubiquinol/ubiquinone) actually increased superoxide production by bovine aortic endothelial (BAE) cell mitochondria incubated with complex I but not complex II substrates. METHODS AND RESULTS: To furt...

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Autores principales: Fink, Brian D., O'Malley, Yunxia, Dake, Brian L., Ross, Nicolette C., Prisinzano, Thomas E., Sivitz, William I.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2009
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2621344/
https://ncbi.nlm.nih.gov/pubmed/19158951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004250
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