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Pleiotropic effects of statin therapy: molecular mechanisms and clinical results
Statins inhibit the enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, which is required for cholesterol biosynthesis, and are beneficial in the primary and secondary prevention of cardiovascular disease. Most of the benefits of statin therapy are owing to the lowering of serum choles...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2621332/ https://ncbi.nlm.nih.gov/pubmed/18068482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2007.11.004 |
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