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Drosophila PCH2 Is Required for a Pachytene Checkpoint That Monitors Double-Strand-Break-Independent Events Leading to Meiotic Crossover Formation
During meiosis, programmed DNA double-strand breaks (DSBs) are repaired to create at least one crossover per chromosome arm. Crossovers mature into chiasmata, which hold and orient the homologous chromosomes on the meiotic spindle to ensure proper segregation at meiosis I. This process is usually mo...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2621188/ https://ncbi.nlm.nih.gov/pubmed/18957704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.093112 |
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