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A role for Ddc1 in signaling meiotic double-strand breaks at the pachytene checkpoint

The pachytene checkpoint prevents meiotic cell cycle progression in response to unrepaired recombination intermediates. We show that Ddc1 is required for the pachytene checkpoint in Saccharomyces cerevisiae. During meiotic prophase, Ddc1 localizes to chromosomes and becomes phosphorylated; these eve...

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Bibliografiske detaljer
Main Authors: Hong, Eun-Jin Erica, Roeder, G. Shirleen
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC155327/
https://ncbi.nlm.nih.gov/pubmed/11825877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.938102
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