A role for Ddc1 in signaling meiotic double-strand breaks at the pachytene checkpoint
The pachytene checkpoint prevents meiotic cell cycle progression in response to unrepaired recombination intermediates. We show that Ddc1 is required for the pachytene checkpoint in Saccharomyces cerevisiae. During meiotic prophase, Ddc1 localizes to chromosomes and becomes phosphorylated; these eve...
Spremljeno u:
| Izdano u: | Genes Dev |
|---|---|
| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cold Spring Harbor Laboratory Press
2002
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC155327/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11825877/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.938102 |
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