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The C-Terminal Domain of ERp29 Mediates Polyomavirus Binding, Unfolding, and Infection

Penetration of the endoplasmic reticulum (ER) membrane by polyomavirus (PyV) is a decisive step in virus entry. We showed previously that the ER-resident factor ERp29 induces the local unfolding of PyV to initiate the ER membrane penetration process. ERp29 contains an N-terminal thioredoxin domain (...

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Detalhes bibliográficos
Main Authors: Rainey-Barger, Emily K., Mkrtchian, Souren, Tsai, Billy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2620899/
https://ncbi.nlm.nih.gov/pubmed/19019959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02057-08
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