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Specific Inhibition of the PKR-Mediated Antiviral Response by the Murine Cytomegalovirus Proteins m142 and m143

Double-stranded RNA (dsRNA) produced during viral infection activates several cellular antiviral responses. Among the best characterized is the shutoff of protein synthesis mediated by the dsRNA-dependent protein kinase (PKR) and the oligoadenylate synthetase (OAS)/RNase L system. As viral replicati...

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Hlavní autoři: Budt, Matthias, Niederstadt, Lars, Valchanova , Ralitsa S., Jonjić, Stipan, Brune, Wolfram
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2620897/
https://ncbi.nlm.nih.gov/pubmed/19019949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01558-08
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