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Mechanism of mda-5 Inhibition by Paramyxovirus V Proteins
The RNA helicases encoded by melanoma differentiation-associated gene 5 (mda-5) and retinoic acid-inducible gene I (RIG-I) detect foreign cytoplasmic RNA molecules generated during the course of a virus infection, and their activation leads to induction of type I interferon synthesis. Paramyxoviruse...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2620892/ https://ncbi.nlm.nih.gov/pubmed/19019954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01768-08 |
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